基于双光子显微镜的纤维傅立叶变换
蔡凡,朱同波
(闽南理工学院,福建 泉州 362700)
摘要:基于双光子显微镜的基本原理,主要针对乳腺组织中癌细胞入侵正常细胞,对胶原纤维的形态特征进行提取分析,使用MATLAB编程实现该过程中图像的处理。通过对病变纤维图片的频谱信息特征进行提取和分析,统计频谱图各个方向上灰度值概率,判断癌细胞的入侵时,纤维的排列取向变化的信息。该计算机诊断技术即可以判断癌细胞是否开始入侵及入侵的程度,在癌症诊断上具有重要意义。
关键词:双光子;胶原纤维;傅立叶变换;癌症
中图分类号:R814.43            文献标识码:A         文章编号:1006-0316 (2013) 05-0030-06
Fiber fourier transform based on the two-photon microscope
CAI Fan,ZHU Tong-bo
( Minnan University of Science and Technology, Quanzhou 362700, China )
Abstract:This paper based on the basic principle of two-photon microscope, mainly for breast cancer tissue invasion of normal cells, the collagen fiber morphological and physiological characteristics extraction analysis, the use of MATLAB programming to realize the process of image processing. Through the lesions of the frequency spectrum of fiber image information features extraction and analysis, statistics spectrum diagram in all directions gray value probability, judge cancer invasion, fiber arrangement orientation change information. The computer diagnostic technique that can judge whether the cancer cells began to invade and invasion degree in cancer diagnosis is of great significance.
Key words:two-photon;collagen fiber;Fourier transform;cancer

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收稿日期:2012-11-06
基金项目:福建泉州市科技计划项目(z[2013]0157)
作者简介:蔡凡(1986-),女,湖北黄冈人,本科,助教,主要研究方向为电子通信工程;朱同波(1986-),男,黑龙江牡丹江人,本科,助教,主要研究方向为机械设计制造。
 

 

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